Changes of Ghrelin/GOAT axis and mTOR pathway in the hypothalamus after sleeve gastrectomy in obese type-2 diabetes rats

Figure 5 Oral glucose tolerance test curve of blood insulin at the first day (A), preoperatively (B) and postoperatively (C) and AUC-blood insulin (D). Statistical differences among the three groups at the same time point were analyzed by one-way ANOVA followed by LSD-t test and between two time points in one group using paired t test. ^aP < 0.05, SG vs S0 and Sh at the same time point; ^cP < 0.05, preoperative or postoperative vs first day levels in the same group; ^eP < 0.05, postoperative vs preoperative levels in the SG group; ^gP < 0.05, SG vs S0 and Sh postoperatively. OGTT: Oral glucose tolerance test; Sh: Sham operation group; SG: Sleeve gastrectomy; LSD: Least significant difference.