Drainage fluid and serum amylase levels accurately predict development of postoperative pancreatic fistula

Table 4 Results of univariate analysis showing risk factors for postoperative pancreatic fistula

Factor	β	SE	Waldχ2	OR (95%CI)	P value
Age in yr	0.023	0.037	0.397	1.024 (0.952-1.101)	0.529
Sex, female/male	-0.586	0.500	1.375	0.557 (0.209-1.482)	0.241
Blood loss in mL	0.000	0.001	0.257	1.000 (0.999-1.001)	0.612
Pancreatic duct diameter,	-0.841	0.475	3.135	0.431 (0.170-1.094)	0.077
> 3 mm/< 3 mm
Preoperative low plasma protein, yes/no	0.178	0.545	0.106	1.194 (0.410-3.476)	0.744
Preoperative relief of jaundice, yes/no	0.754	0.749	1.012	2.125 (0.489-9.227)	0.314
Preoperative jaundice, yes/no	0.106	0.482	0.048	1.112 (0.432-2.861)	0.826
Internal or External drainage of PD	0.251	0.468	0.289	1.286 (0.514-3.214)	0.591
Diabetes, yes/no	21.952	28420.722	0.000	3.417E9 (0.000)	0.999
Pathology examination result, ampullary carcinoma/pancreatic carcinoma/cholangiocarcinoma	0.241	0.182	1.757	1.273 (0.891-1.819)	0.185
Duration of surgery in min	0.000	0.003	0.008	1.000 (0.995-1.005)	0.928
Drainage fluid amylase level, POD1 > 5000 U/L	0.000	0.000	10.293	1.000 (1.000--1.000)	0.001
Serum amylase level
POD1 > 140 U/L	0.004	0.001	9.982	1.004 (1.001-1.006)	0.002
POD4 > 140 U/L	0.013	0.005	7.752	1.013 (1.004-1.022)	0.005
Serum albumin
POD1	0.000	0.045	0.000	1.000 (0.916, 1.092)	0.994
POD3	-0.006	0.044	0.020	0.994 (0.911, 1.084)	0.887
POD5	-0.023	0.044	0.277	0.977 (0.897, 1.064)	0.599
Choline
POD1	-0.016	0.041	0.149	0.984 (0.908, 1.067)	0.700
POD3	0.033	0.046	0.521	1.034 (0.945, 1.131)	0.470
POD5	0.007	0.053	0.016	1.007 (0.908, 1.117)	0.898
WBC count
POD1	0.000	0.000	1.153	1.000 (1.000, 1.000)	0.283
POD3	0.000	0.000	1.298	1.000 (0.999, 1.000)	0.255
POD5	0.000	0.000	2.026	1.000 (0.999, 1.000)	0.155

POPF: Postoperative pancreatic fistula; PD: Pancreaticoduodenectomy; WBC: White blood cell; POD: Postoperative day.