Natural history of covert hepatic encephalopathy: An observational study of 366 cirrhotic patients

Table 3 Cox analysis of predictors for developing overt hepatic encephalopathy, the first cirrhosis-related complications requiring hospitalization, and mortality in 131 covert hepatic encephalopathy patients

	Predictor(s)	β	HR	95%CI	P value
For developing OHE	Albumin < 30 g/L	1.65	5.22	1.22-22.32	0.03
For developing the first cirrhosis-related complications	Cr > 133 μmol/L	1.24	3.46	1.46-8.20	0.005
	MELD score > 20	2.31	10.12	4.14-24.74	< 0.001
	PLT < 80 × 109/L	2.52	2.44	1.69-6.60	0.013
For mortality	Cr > 133 μmol/L	1.51	4.75	1.10-20.44	0.036

Cr: Creatinine; MELD: Model for end-stage liver disease; OHE: Overt hepatic encephalopathy; PLT: Platelet.