Systemic immune-inflammation index for predicting prognosis of colorectal cancer

Table 3 Univariate and multivariate Cox regression analysis of the associations between clinical parameters and PFS in patients with colorectal cancer

	Univariate analysis				Multivariate analysis
	χ2 value	HR	95%CI	P value	χ2 value	HR	95%CI	P value
Age	21.774	1.373	1.202-1.569	< 0.001	34.479	1.499	1.310-1.716	< 0.001
Gender	0.144	-	-	0.705
Tumor location	0.509	-	-	0.476
Histological type	20.091	1.447	1.231-1.701	< 0.001
Tumor size	1.095	-	-	0.295
T stage	59.847	1.419	1.299-1.550	< 0.001
N stage	86.718	1.354	1.270-1.443	< 0.001
M stage	221.926	3.172	2.725-3.692	< 0.001	31.580	2.024	1.583-2.589	< 0.001
TNM stage	179.589	1.673	1.552-1.804	< 0.001	15.414	1.255	1.121-1.406	< 0.001
NLR status	36.441	1.518	1.325-1.738	< 0.001
PLR status	20.826	1.369	1.196-1.567	< 0.001
SII status	159.123	2.988	2.521-3.542	< 0.001	129.495	2.717	2.287-3.228	< 0.001
Chemotherapy	61.159	1.716	1.499-1.965	< 0.001

NLR: Neutrophil-lymphocyte ratio; PLR: Platelet-lymphocyte ratio.