Systemic immune-inflammation index for predicting prognosis of colorectal cancer

Table 2 Univariate and multivariate Cox regression analysis of the associations between clinical parameters and overall survival in patients with colorectal cancer

	Univariate analysis				Multivariate analysis
	χ2 value	HR	95%CI	P value	χ2 value	HR	95%CI	P value
Age	22.965	1.405	1.223-1.614	< 0.001	38.131	1.561	1.355-1.798	< 0.001
Gender	0.017	-	-	0.896
Tumor location	0.269	-	-	0.604
Histological type	22.178	1.493	1.264-1.764	< 0.001
Tumor size	1.166	-	-	0.280
T stage	71.702	1.498	1.364-1.645	< 0.001
N stage	113.905	1.432	1.340-1.529	< 0.001
M stage	239.937	3.415	2.923-3.989	< 0.001	26.390	1.951	1.512-2.517	< 0.001
TNM stage	207.252	1.785	1.650-1.932	< 0.001	22.971	1.345	1.191-1.518	< 0.001
NLR status	40.824	1.582	1.374-1.821	< 0.001
PLR status	23.604	1.416	1.231-1.649	< 0.001	12.618	1.294	1.123-1.492	< 0.001
SII status	173.330	3.529	2.925-4.258	< 0.001	141.427	3.163	2.616-3.824	< 0.001
Chemotherapy	76.931	1.894	1.642-2.184	< 0.001

NLR: Neutrophil-lymphocyte ratio; PLR: Platelet-lymphocyte ratio.