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©The Author(s) 2017.
World J Gastroenterol. Sep 14, 2017; 23(34): 6261-6272
Published online Sep 14, 2017. doi: 10.3748/wjg.v23.i34.6261
Published online Sep 14, 2017. doi: 10.3748/wjg.v23.i34.6261
Table 1 Baseline patient characteristics based on neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and systemic immune-inflammation index n (%)
| Cases | NLR | P value | PLR | P value | SII | P value | ||||
| ≤ 2.7 | > 2.7 | ≤ 210 | > 210 | ≤ 340 | > 340 | |||||
| Age (yr) | 0.005 | 0.904 | 0.063 | |||||||
| ≤ 60 | 698 (50.5) | 480 (53.2) | 218 (45.3) | 437 (50.3) | 261 (50.7) | 233 (54.2) | 465 (48.8) | |||
| > 60 | 685 (49.5) | 422 (46.8) | 263 (54.7) | 431 (49.7) | 254 (49.7) | 197 (45.8) | 488 (51.2) | |||
| Gender | 0.067 | 0.422 | 0.927 | |||||||
| Male | 808 (58.4) | 511 (56.7) | 297 (61.7) | 500 (57.6) | 308 (59.8) | 252 (58.6) | 536 (58.3) | |||
| Female | 575 (41.6) | 391 (43.3) | 184 (38.3) | 368 (42.4) | 207 (40.2) | 178 (41.4) | 397 (41.7) | |||
| Tumor location | < 0.001 | 0.008 | 0.060 | |||||||
| Right-sided | 324 (23.4) | 185 (20.5) | 139 (28.9) | 183 (21.1) | 141 (27.4) | 87 (20.2) | 237 (24.9) | |||
| Left-sided | 1059 (76.6) | 717 (79.5) | 342 (71.1) | 685 (78.9) | 374 (72.3) | 343 (79.8) | 716 (75.1) | |||
| Histological type | < 0.001 | 0.020 | < 0.001 | |||||||
| Well-differentiated | 1126 (81.4) | 761 (84.4) | 365 (75.9) | 723 (83.3) | 403 (78.3) | 376 (87.4) | 750 (78.7) | |||
| Poorly differentiated | 257 (18.6) | 141 (15.6) | 116 (24.1) | 145 (16.7) | 112 (21.7) | 54 (12.6) | 203 (21.3) | |||
| Tumor size | < 0.001 | < 0.001 | 0.003 | |||||||
| ≤ 5 cm | 936 (67.7) | 660 (73.2) | 276 (57.4) | 617 (71.1) | 319 (61.9) | 315 (73.3) | 621 (65.2) | |||
| > 5 cm | 447 (32.3) | 242 (26.8) | 205 (42.6) | 251 (28.9) | 196 (38.1) | 115 (26.7) | 332 (34.8) | |||
| T stage | < 0.001 | < 0.001 | < 0.001 | |||||||
| T1 | 67 (4.8) | 45 (5.0) | 22 (4.6) | 54 (4.9) | 13 (4.8) | 38 (8.8) | 29 (3.0) | |||
| T2 | 256 (18.5) | 197 (21.8) | 59 (12.3) | 170 (19.9) | 86 (16.7) | 104 (24.2) | 152 (15.9) | |||
| T3 | 748 (54.1) | 507 (56.2) | 241 (50.1) | 475 (54.7) | 273 (53.0) | 232 (54.0) | 516 (54.1) | |||
| T4 | 312 (22.6) | 153 (17.0) | 159 (33.1) | 169 (19.5) | 143 (27.8) | 56 (13.0) | 256 (26.9) | |||
| N stage | < 0.001 | 0.021 | < 0.001 | |||||||
| N0 | 487 (35.2) | 353 (39.1) | 134 (27.9) | 325 (37.4) | 162 (31.5) | 196 (45.6) | 291 (30.5) | |||
| N1 | 416 (30.1) | 277 (30.7) | 139 (28.9) | 261 (30.1) | 155 (30.1) | 121 (28.1) | 295 (31.0) | |||
| N2 | 308 (22.3) | 188 (20.8) | 120 (24.9) | 190 (21.9) | 118 (22.9) | 77 (17.9) | 231 (24.2) | |||
| N3 | 172 (12.4) | 84 (9.3) | 88 (18.3) | 92 (10.6) | 80 (15.5) | 36 (8.4) | 136 (14.3) | |||
| M stage | < 0.001 | < 0.001 | < 0.001 | |||||||
| M0 | 1115 (80.6) | 774 (85.8) | 341 (70.9) | 726 (83.6) | 389 (75.5) | 386 (89.8) | 729 (76.5) | |||
| M1 | 268 (19.4) | 128 (14.2) | 140 (29.1) | 142 (16.4) | 126 (24.5) | 44 (10.2) | 224 (23.5) | |||
| TNM stage | < 0.001 | 0.001 | < 0.001 | |||||||
| I | 187 (13.5) | 141 (15.6) | 46 (9.6) | 133 (15.3) | 54 (10.5) | 92 (21.4) | 95 (10.0) | |||
| II | 515 (37.2) | 368 (40.8) | 147 (30.6) | 335 (38.6) | 180 (35.0) | 171 (39.8) | 344 (36.1) | |||
| III | 413 (29.9) | 265 (29.4) | 148 (30.8) | 258 (29.7) | 155 (30.1) | 123 (28.6) | 290 (30.4) | |||
| IV | 268 (19.4) | 128 (14.2) | 140 (29.1) | 142 (16.4) | 126 (24.5) | 44 (10.2) | 224 (23.5) | |||
| Chemotherapy | < 0.001 | < 0.001 | < 0.001 | |||||||
| No | 684 (49.5) | 488 (54.1) | 196 (40.7) | 472 (54.4) | 212 (41.2) | 243 (56.5) | 441 (46.3) | |||
| Yes | 699 (50.5) | 414 (45.9) | 285 (59.3) | 396 (45.6) | 303 (58.8) | 187 (43.5) | 512 (53.7) | |||
- Citation: Chen JH, Zhai ET, Yuan YJ, Wu KM, Xu JB, Peng JJ, Chen CQ, He YL, Cai SR. Systemic immune-inflammation index for predicting prognosis of colorectal cancer. World J Gastroenterol 2017; 23(34): 6261-6272
- URL: https://www.wjgnet.com/1007-9327/full/v23/i34/6261.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i34.6261