Changes of Ghrelin/GOAT axis and mTOR pathway in the hypothalamus after sleeve gastrectomy in obese type-2 diabetes rats

Table 1 Changes in fasting blood glucose

Time points	Fasting blood glucose (mmol/L)
	S0	Sh	SG
First day	6.18 ± 1.19	5.89 ± 1.12	6.19 ± 0.94
Preoperative	15.03 ± 2.4a	15.9 ± 1.2a	15.88 ± 2.32a
Postoperative wk 8	14.55 ± 1.29	14.29 ± 1.69	9.00 ± 1.17ce

Statistical differences among the three groups were analyzed by one-way ANOVA followed by LSD-t and between two time points in one group using a paired t test.

^aP < 0.05, preoperative vs first day levels in the same group;

^cP < 0.05, postoperative vs preoperative levels in the SG group;

^eP < 0.05, SG vs S0 and Sh postoperatively. LSD: Least significant difference; Sh: Sham operation group; SG: Sleeve gastrectomy.