Changes in expression of inhibitory substances in the intramural neurons of the stomach following streptozotocin- induced diabetes in the pig

Figure 1 Myenteric ganglion of the porcine stomach under physiological condition and after streptozotocine treatment immunoreactive to nNOS. A: Myenteric ganglion of the porcine antrum under physiological condition immunoreactive to Hu C/D; B: Myenteric ganglion of the porcine antrum under physiological condition immunoreactive to nNOS; C: Myenteric ganglion of the porcine antrum under physiological condition immunoreactive to Hu C/D and n NOS; D: Myenteric ganglion of the porcine antrum after streptozotocine treatment immunoreactive to Hu C/D; E: Myenteric ganglion of the porcine antrum after streptozotocine treatment immunoreactive to nNOS; F: Myenteric ganglion of the porcine antrum after streptozotocine treatment immunoreactive to Hu C/D and nNOS; G: Myenteric ganglion of the porcine corpus under physiological condition immunoreactive to Hu C/D; H: Myenteric ganglion of the porcine corpus under physiological condition immunoreactive to nNOS; I: Myenteric ganglion of the porcine corpus under physiological condition immunoreactive to Hu C/D and nNOS; J: Myenteric ganglion of the porcine corpus after streptozotocine treatment immunoreactive to Hu C/D; K: Myenteric ganglion of the porcine corpus after streptozotocine treatment immunoreactive to nNOS; L: Myenteric ganglion of the porcine corpus after streptozotocine treatment immunoreactive to Hu C/D and nNOS; M: Myenteric ganglion of the porcine pylorus under physiological condition immunoreactive to Hu C/D; N: Myenteric ganglion of the porcine pylorus under physiological condition immunoreactive to nNOS; O: Myenteric ganglion of the porcine pylorus under physiological condition immunoreactive to Hu C/D and nNOS; P: Myenteric ganglion of the porcine pylorus after streptozotocine treatment immunoreactive to Hu C/D; R: Myenteric ganglion of the porcine pylorus after streptozotocine treatment immunoreactive to nNOS; S: Myenteric ganglion of the porcine corpus after streptozotocine treatment immunoreactive to Hu C/D and nNOS. The right column of the pictures shows the overlap of both stainings. Colocalization of both antigens in the studied cell bodies are indicated with arrows. nNOS: Neuronal isoform of nitric oxide synthase; Hu C/D: Pan-neuronal marker.