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©The Author(s) 2017.
World J Gastroenterol. Sep 7, 2017; 23(33): 6065-6076
Published online Sep 7, 2017. doi: 10.3748/wjg.v23.i33.6065
Published online Sep 7, 2017. doi: 10.3748/wjg.v23.i33.6065
Figure 5 Effect of guanylate cyclase C agonism on gastric ulcer pain.
A: Dose-response and time course for the effect of linaclotide on referred gastric ulcer pain. Linaclotide significantly attenuated referred gastric ulcer pain when dosed 3-10 μg/kg. Data are expressed as the mean SEM where n = 9-10 mice/group. aP < 0.05 vs vehicle, cP < 0.05 vs indomethacin.
- Citation: Hummel M, Knappenberger T, Reilly M, Whiteside GT. Pharmacological evaluation of NSAID-induced gastropathy as a "Translatable" model of referred visceral hypersensitivity. World J Gastroenterol 2017; 23(33): 6065-6076
- URL: https://www.wjgnet.com/1007-9327/full/v23/i33/6065.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i33.6065