Pharmacological evaluation of NSAID-induced gastropathy as a "Translatable" model of referred visceral hypersensitivity

Figure 4 Effect of acid-sensing ion channels channel blockade on gastric ulcer pain. Dose-response and time course for the effect of non-selective ASIC channel blockade on referred gastric ulcer pain. Amiloride did not attenuate referred gastric ulcer pain at any of the doses tested. Data are expressed as the mean SEM where n = 10 mice/group. ^aP < 0.05 vs vehicle.