Suspicious brush cytology is an indication for liver transplantation evaluation in primary sclerosing cholangitis

Table 3 Brush cytology and DNA flow cytometry in patients with low-grade dysplasia, high-grade dysplasia or cholangiocarcinoma

	LGD	HGD	CCA	P value
Patients, n	16	10	19
Liver transplanted, n	16	10	4
BCs, n (IQR)	4.0 (2.3-5.0)	4.5 (1.8-5.3)	2.5 (1.8-5.3)	0.219
BC suspicious/malignant	11	8	15	0.746
Flow cytometry, n (IQR)	3.0 (2.3-4.0)	3.0 (1.8-5.0)	2.0 (1.0-4.3)	0.195
DNA-index (highest, IQR)	1.0 (1.0-1.2)	1.2 (1.0-1.8)	1.0 (1.0-1.2)	0.745
Aneuploid	6	5	7	0.795

Numbers are median (IQR) or n. P values: Jonckeere-Terpstra test for continuous variables, and Fisher's exact test for dichotomous variables. BC: Brush cytology; CCA: Cholangiocarcinoma; HGD: High-grade dysplasia; IQR: Interquartile rate; LGD: Low-grade dysplasia.