HOX transcript antisense intergenic RNA represses E-cadherin expression by binding to EZH2 in gastric cancer

Table 2 Univariate and multivariate analysis of clinical pathological characteristics and overall survival of 65 patients with gastric cancer

Factor	Univariate analysis			Multivariate analysis
	HR	95%CI	P value	HR	95%CI	P value
HOTAIR expression	2.943	1.580-5.483	0.001	1.998	1.058-3.772	0.033
Tumor invasion depth, T1, T2/above	2.651	1.316-5.341	0.006	1.676	0.691-4.067	0.254
Lymphatic metastasis, absent/present	3.470	1.459-8.250	0.005	4.324	1.701-10.993	0.002
TNM stage, I/II, III/IV	4.494	2.351-8.592	< 0.001	3.598	1.624-7.975	0.002
Histology grade, well, moderate/others	0.967	0.535-1.750	0.913
Age, < 60/> 60	0.730	0.396-1.344	0.312
Sex, male/female	0.822	0.428-1.581	0.557
Tumor location	0.839	0.623-1.131	0.250
Lauren’s classification	1.256	0.757-2.084	0.378