Copyright
©The Author(s) 2017.
World J Gastroenterol. Sep 7, 2017; 23(33): 6030-6048
Published online Sep 7, 2017. doi: 10.3748/wjg.v23.i33.6030
Published online Sep 7, 2017. doi: 10.3748/wjg.v23.i33.6030
Prednisone mg/kg/d | Azathioprine | |
Week 1 | 2.0 | Check transaminase levels every week before reducing the prednisone dose: if transaminase levels stop decreasing, add azathioprine starting with 0.5 mg/kg per day, if jaundice is subsiding, at increasing doses up to 2-2.5 mg/kg/d until biochemical control |
Week 2 | 1.75 | |
Week 3 | 1.50 | |
Week 4 | 1.25 | |
Week 5 | 1.00 | |
Week 6 | 0.75 | |
Week 7 | 0.50 | |
Week 8-9 | 0.25 | |
Week 10-11 | 0.10-0.20 | |
If severe steroid side effects: consider reducing to 2.5 mg/d for 2 wk and then stopping prednisone |
- Citation: Terziroli Beretta-Piccoli B, Mieli-Vergani G, Vergani D. Autoimmune hepatitis: Standard treatment and systematic review of alternative treatments. World J Gastroenterol 2017; 23(33): 6030-6048
- URL: https://www.wjgnet.com/1007-9327/full/v23/i33/6030.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i33.6030