Changes with aging in gastric biomarkers levels and in biochemical factors associated with Helicobacter pylori infection in asymptomatic Chinese population

Figure 1 Comparison of serum gastric biomarker levels in various age groups. There was no significant difference in serum levels of PGI and G-17 between each age group with increasing age. In contrast, serum levels of PGII increased with age, and were significantly higher in subjects ≥ 65-years-old compared to 35-44-years-old group. The ratio of PGI/PGII decreased with age, and was significantly lower in subjects ≥ 75-years-old compared to 35-44-years-old group. The “a” denotes comparison with 35-44-years-old age group, ^aP < 0.05, ^bP < 0.01. G-17: Gastrin-17; PGI: Pepsinogen I; PGII: Pepsinogen II.