Changes with aging in gastric biomarkers levels and in biochemical factors associated with Helicobacter pylori infection in asymptomatic Chinese population

Table 1 Comparison of serum gastric biomarker levels in various age groups

	35-44 yr, n = 58	45-54 yr, n = 84	55-64 yr, n = 117	65-74 yr, n = 76	≥ 75 yr, n = 60	F	P value
PGI, μg/L	92.98 ± 5.16	98.47 ± 4.15	98.65 ± 3.66	108.56 ± 8.01	117.04 ± 8.30	2.326	0.056
PGII, μg/L	9.65 ± 0.73	12.26 ± 0.91	12.43 ± 0.76	14.23 ± 1.171a	15.33 ± 1.251b	3.915	0.004
PGI/PGII	10.94 ± 0.44	9.89 ± 0.40	9.67 ± 0.36	9.29 ± 0.61	8.71 ± 0.521a	2.407	0.049
G-17, pmol/L	2.93 ± 0.55	5.10 ± 1.29	5.75 ± 1.49	9.93 ± 3.00	10.03 ± 3.18	1.950	0.101

Data are presented as mean ± SD.

¹Comparison with the 35-44-years-old group,

^aP < 0.05,

^bP < 0.01. G-17: Gastrin-17; PGI: Pepsinogen I; PGII: Pepsinogen II.