Integrating TYMS, KRAS and BRAF testing in patients with metastatic colorectal cancer

doi:10.3748/wjg.v23.i32.5913

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2017; 23(32): 5913-5924
Published online Aug 28, 2017. doi: 10.3748/wjg.v23.i32.5913

Table 1 Thymidylate synthase polymorphisms’ groups per untranslated region

	Low expression	Medium expression	High expression
TYMS 3’UTR	del/del	ins/del	ins/ins
TYMS 3’UTR		del/LOH	ins/LOH
TYMS 5’UTR	2RG	2RG/3RG	3RG
	2RG/3RC	2RG/3RG	3RG/3RC
	3RC	2RG/3RCLOH	2RGLOH/3RG
		2RG/3RGLOH
		2RGLOH/3RC

LOH: Loss of heterozygosity; UTR: Untranslated region.

Citation: Ntavatzikos A, Spathis A, Patapis P, Machairas N, Peros G, Konstantoudakis S, Leventakou D, Panayiotides IG, Karakitsos P, Koumarianou A. Integrating TYMS, KRAS and BRAF testing in patients with metastatic colorectal cancer. World J Gastroenterol 2017; 23(32): 5913-5924
URL: https://www.wjgnet.com/1007-9327/full/v23/i32/5913.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i32.5913