Nano albumin bound-paclitaxel in pancreatic cancer: Current evidences and future directions

doi:10.3748/wjg.v23.i32.5875

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2017; 23(32): 5875-5886
Published online Aug 28, 2017. doi: 10.3748/wjg.v23.i32.5875

Table 3 Principal clinical trials with nab-paclitaxel in pancreatic cancer “early settings”

Study ID	Setting	Study drugs	Phase	Status
NCT01964430	Adjuvant	Nab-paclitaxel + Gemcitabine vs Gemcitabine	III	Recruiting
NCT02506842	Adjuvant	Nab-paclitaxel + Gemcitabine vs OFF	III	Recruiting
NCT02023021	Adjuvant	Nab-paclitaxel + Gemcitabine	II	Recruiting
NCT02125136	Neoadjuvant	Nab-paclitaxel + Gemcitabine vs FOLFIFINOX	II	Recruiting
NCT02243007	Neoadjuvant	Nab-paclitaxel + Gemcitabine vs FOLFIFINOX	II	Recruiting
NCT02717091	Neoadjuvant/borderline resectable	Nab-paclitaxel + Gemcitabine vs FOLFIFINOX	II	Recruiting
NCT02481635	NEO/adjuvant	Nab-paclitaxel + Gemcitabine + radiotherapy	I-II	Recruiting
NCT01431794	Neoadjuvant	Nab-paclitaxel + Gemcitabine + LDE-225	I-II	Active not recruiting
NCT02588443	NEO/adjuvant	Nab-paclitaxel + Gemcitabine + RO7009789	I	Recruiting
NCT02272738	Neoadjuvant	Nab-paclitaxel + Gemcitabine + radiotherapy	I	Recruiting
NCT02506803	Neoadjuvant	Nab-paclitaxel + Gemcitabine	I	Recruiting
NCT02427841	Resectable	Nab-paclitaxel + Gemcitabine followed by radiotherapy	II	Recruiting
NCT02550327	Resectable	Nab-paclitaxel + Gemcitabine + Cisplatin + Anakinra	I	Recruiting
NCT02210559	Locally advanced	Nab-paclitaxel + Gemcitabine + FG-3019	I-II	Recruiting
NCT02394535	Locally advanced	Nab-paclitaxel + Capecitabine + radiotherapy	I	Recruiting
NCT02124369	Borderline unresectable	Nab-paclitaxel + Gemcitabine	II	Recruiting
NCT02043730	Unresectable locally advaced	Nab-paclitaxel + Gemcitabine	II	Recruiting
NCT02207465	Unresectable locally advanced	Nab-paclitaxel + Gemcitabine + radiotherapy	I	Recruiting
NCT02272738	Unresectable locally advanced	Nab-paclitaxel + Gemcitabine	I	Recruiting
NCT01978184	Preoperative	Nab-paclitaxel + Gemcitabine + Hydroxychloroquine	II	Recruiting
NCT02427841	Preoperative	Nab-paclitaxel + Gemcitabine + radiotherapy	II	Recruiting
NCT02723331	Preoperative	Nab-paclitaxel + Gemcitabine followed by SBRT	II	Recruiting
NCT02930902	Preoperative	Nab-paclitaxel + Gemcitabine + Pembrolizumab + Paricalcitol	I	Recruiting

SBRT: Stereotactic body radiotherapy; OFF: Oxaliplatin plus fluoro-folate.

Citation: Giordano G, Pancione M, Olivieri N, Parcesepe P, Velocci M, Di Raimo T, Coppola L, Toffoli G, D’Andrea MR. Nano albumin bound-paclitaxel in pancreatic cancer: Current evidences and future directions. World J Gastroenterol 2017; 23(32): 5875-5886
URL: https://www.wjgnet.com/1007-9327/full/v23/i32/5875.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i32.5875