Nano albumin bound-paclitaxel in pancreatic cancer: Current evidences and future directions

doi:10.3748/wjg.v23.i32.5875

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2017; 23(32): 5875-5886
Published online Aug 28, 2017. doi: 10.3748/wjg.v23.i32.5875

Table 1 Patients characteristics in metastatic pancreatic cancer pivotal trials

	Gemcitabine	FOLFIRINOX	Nab-paclitaxel + gemcitabine
Trial (yr)	Gemcitabine vs 5-fluorouracil (1997)	FOLFIRINOX vs Gemcitabine (2011)	Nab-paclitaxel + Gemcitabine vs Gemcitabine (2013)
Phase	¹	II-III	III
Countries	United states-Canada-United Kingdom	France	Worldwide
Patients	126	342	861
Median age	61.5	61	62
Elderly ( ≥ 75 yr)	Yes		Yes
ECOG PS 0-1	Yes	Yes	Yes
ECOG PS 2	Yes		Yes
Biliary Stent	Yes	Yes	Yes
Multiple metastatic sites	Yes	Yes	Yes

¹Phase not specified in the full paper. ECOG PS: Eastern Cooperative Oncology Group Performance Status.

Citation: Giordano G, Pancione M, Olivieri N, Parcesepe P, Velocci M, Di Raimo T, Coppola L, Toffoli G, D’Andrea MR. Nano albumin bound-paclitaxel in pancreatic cancer: Current evidences and future directions. World J Gastroenterol 2017; 23(32): 5875-5886
URL: https://www.wjgnet.com/1007-9327/full/v23/i32/5875.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i32.5875