Cytoplasmic domain of tissue factor promotes liver fibrosis in mice

Figure 4 TGFβ mRNA and protein expression. A: TGFβ mRNA expression was significantly lower in the TF§^CT/§CT group with a similar but non-significant trend in TF^§CT/§CT/PAR-2^-/- mice compared to wildtype. Levels were similar to PAR-2 KO mice, which were also significantly lower than WT; B: TGFβ protein was significantly lower in TF^§CT/§CT, TF^§CT/§CT/PAR-2^-/- and PAR-2^-/- mice compared to wildtype with levels similar to vehicle controls. ^cP < 0.001, ^dP < 0.0001. ns: Not significant.