Tegafur-uracil-induced rapid development of advanced hepatic fibrosis

Table 2 Tegafur-uracil-induced hepatic fibrosis

Cases	Age (yr)	Sex	Daily dose (mg)	Duration (mo)	Type 4 collagen 7S (ng/mL)	Hepatic fibrosis	Portal hypertension
1[1]	81	M	400	48	12	Bridging fibrosis	Esophageal varices
							Ascites
2[3]	76	F	NA	24	NA	Bridging fibrosis	Ascites
3[4]	82	M	300	48	12	Bridging fibrosis	NA
4[4]	73	M	300	23	11	Bridging fibrosis	NA
5[4]	68	F	400	55	12	Bridging fibrosis	NA
Our case	74	F	400	8	16	Bridging fibrosis	Esophageal varices
						With septation	Ascites
							Splenomegaly

M: Male; F: Female; NA: Not available.