Threonine and tyrosine kinase may serve as a prognostic biomarker for gallbladder cancer

Table 5 Univariate and multivariate analyses for gallbladder cancer

	χ2	P value	OR (95%CI)
Univariate
Age	2.221	0.136
Gender	0.167	0.683
Cholecystolithiasis	0.346	0.558
Diabetes	0.165	0.685
Fever	0.001	0.989
Jaundice1	5.110	0.0241
ALT1	7.781	0.0051
AST1	5.708	0.0171
TBil	0.241	0.516
DBil1	6.645	0.0101
GGT	0.899	0.343
ALP1	4.099	0.0431
CEA	3.137	0.077
CA 19-91	12.385	< 0.0011
Surgical type1	20.715	< 0.0011
Tumor size	0.099	0.754
Differentiation1	12.385	< 0.0011
T stage1	21.594	< 0.0011
N stage1	19.887	< 0.0011
M stage1	29.503	< 0.0011
TNM stage1	33.062	< 0.0011
TTK1	21.226	< 0.0011
Multivariate
Surgery type1		0.0011	4.250 (1.867-9.674)
T stage1		0.0131	2.927 (1.258-6.808)
TTK1		0.0011	0.076 (0.024-0.241)

¹Statistically significant. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transpeptidase; CEA: Carcinoembryonic antigen; TTK: Threonine and tyrosine kinase.