Threonine and tyrosine kinase may serve as a prognostic biomarker for gallbladder cancer

Table 2 Threonine and tyrosine kinase staining results in tumor and normal tissues

Localization	Positive cell rate (%)		n (%)
	Median (range)
	Tumor tissues	Normal tissues	Tumor tissues	Normal tissues
Cytoplasmic staining
Negative	-	-	0	0
Positive	100 (10-100)	99 (40-100)	68 (100)	68 (100)
1+	55 (10-100)	85 (18-100)	41 (60.3)	14 (20.6)
2+	90 (5-100)	100 (80-100)	49 (72.1)	54 (79.4)
3+	20	90	1 (1.5)	1 (1.5)
Nuclear staining
Negative	-	-	8 (11.8)	2 (2.9)
Positive	15 (1-98)	60 (1-90)	60 (88.2)	66 (97.1)
1+	15 (1-85)	60 (1-90)	57 (83.8)	59 (86.8)
2+	45 (5-98)	90 (60-90)	8 (11.8)	7 (10.3)
3+	-	-	0	0