Minor endoscopic sphincterotomy followed by large balloon dilation for large choledocholith treatment

Table 3 Univariate analysis of risk factors for post-endoscopic retrograde cholangiopancreatography pancreatitis and stone recurrence

Variable	PEP	No-PEP	P value	Stone recurrence n = 7	No-stone recurrence n =142	P value
	n =13	n =136
Age in yr	60.3 ± 10.7	61.1 ± 11.3	0.8069	59.6 ± 11.4	60.7 ± 9.9	0.7760
Sex, male/female	8/5	84/52	0.7775	5/2	87/55	0.8873
Cholecystolithiasis	2 (15.4)	39 (28.7)	0.4838	1 (14.3)	40 (28.2)	0.7118
History of cholecystectomy	1 (7.7)	13 (9.6)	0.7817	1 (14.3)	14 (9.9)	0.5319
Periampullary diverticulum	0	20 (14.7)	0.2891	2 (28.6)	18 (12.7)	0.2378
Billroth II gastrectomy	1 (7.7)	4 (2.9)	0.3706	0	5 (3.5)	1.0000
Procedure time in min	51.3 ± 11.7	43.6 ± 12.5	0.0346	50.1 ± 10.8	48.1 ± 11.1	0.6420
Maximum CBD diameter in mm	17.1 ± 5.3	16.7 ± 4.9	0.7804	18.7 ± 8.1	16.7 ± 7.7	0.5043
Maximum stone diameter in mm	17.3 ± 5.1	16.9 ± 6.1	0.8194	19.9 ± 7.7	15.3 ± 5.1	0.0246
≥ 16	7 (53.8)	23 (16.9)	0.0049	4 (57.1)	26 (18.3)	0.0435
≥ 22	2	3	0.0607	1 (14.3)	4 (2.8)	0.2165
No. of CBD stones	2.4 ± 1.2	2.2 ± 1.0	0.4995	2.1 ± 1.1	1.9 ± 1.0	0.6071
MLT performed	3 (23.1)	16 (11.7)	0.4635	4 (57.1)	15 (10.6)	0.0053
Dilating procedure performed	6 (46.2)	67 (49.3)	0.8303	4 (57.1)	69 (48.6)	0.6586
ENBD placement time in d	2.3 ± 0.5	2.6 ± 0.7	0.0960	2.8 ± 0.7	2.6 ± 0.7	0.5010

Data are presented as n (%) or mean ± SD. CBD: Common bile duct; ENBD: Endoscopic nasobiliary drainage; EPLBD: Endoscopic papillary large balloon dilation; mEST: Minor endoscopic sphincterotomy; MLT: Mechanical lithotripsy; PEP: Post-endoscopic retrograde cholangiopancreatography pancreatitis.