Expression of Interleukin-26 is upregulated in inflammatory bowel disease

Figure 3 Immunohistochemical analyses of interleukin-26 receptor expression in normal and active/inactive inflammatory bowel disease mucosa. A: Dual-colored immunofluorescence was used to localize α-SMA (red fluorescence) and IL-26 receptor, IL-10R2 and IL-20R1 (green fluorescence). Dual positive immunostaining can be seen as yellow fluorescence in the merged images. Pictures are shown from one of four independent samples with similar results. Magnification × 200; B: The expression of IL-26 receptor in human colonic SEMFs isolated from four different surgical samples. The expression of IL-26 receptor was evaluated by RT-PCR. SMA: Smooth muscle actin; IL: Interleukin; SEMFs: Subepithelial myofibroblasts.