Everolimus halts hepatic cystogenesis in a rodent model of polycystic-liver-disease

Figure 2 Liver volume measurements. A: Demonstration of liver volume measured by MRI on each liver-containing slice of T2 weighted images. The liver margin is contoured manually with the red line; B: Correlation between liver volume calculated from MRI scan and liver volume measured ex vivo. Pearson correlation (r) is given together with significance; C: Liver volume (mean ± SE) determined by MRI for the different groups: CON (controls, n = 14), LAN (n = 10) and EVR (n = 7), measured at start of treatment, and after 8 and 12 wk. ^aP < 0.05 vs animals in control group at corresponding time, NS: Not significant, vs control. The percentual change in LV (ΔLV) over the 12 wk experimental period is shown together with the P value vs control group. LAN: Lanreotide; EVR: Everolimus.