Postoperative bleeding in patients on antithrombotic therapy after gastric endoscopic submucosal dissection

Table 2 Univariate analysis of risk factors of delayed bleeding n (%)

	n = 2378	Delayed bleeding		P value	OR	95%CI
		(+) n = 122	(-) n = 2256
Age (mean ± SD, yr)		71.5 ± 8.7	71.1 ± 8.8	0.6222	1.005	0.984-1.027
Gender
Male	1786 (75.1)	106 (5.9)	1680 (94.1)	0.0021	2.271	1.331-3.875
Female	24.9 (592)	16 (2.7)	576 (97.3)
Location
U	412 (17.3)	17 (4.1)	395 (95.9)		Reference	1.0
M	742 (31.2)	40 (5.4)	702 (94.6)	0.342	1.303	0.755-2.250
L	1224 (51.5)	65 (5.3)	1159 (94.7)	0.344	1.324	0.741-2.366
Morphology
Protruded	1042 (43.8)	49 (4.7)	993 (95.3)	0.4041	0.854	0.589-1.238
Flat/depressed	1336 (56.2)	73 (5.5)	1263 (94.5)
Specimen size (mean ± SD, mm)	38.9 ± 2.2	44.4 ± 15.1	38.9 ± 13.1	< 0.0012	1.025	1.014-1.037-
Depth of invasion
M	2227 (93.7)	109 (4.9)	2118 (95.1)	0.0451	1.830	1.004-3.336
SM	151 (6.3)	13 (8.6)	138 (91.4)
Ulcerative findings
(+)	203 (8.5)	12 (5.9)	191 (94.1)	0.5981	1.179	0.638-2.179
(-)	2175 (91.5)	110 (5.1)	2065 (94.9)
Anticoagulant agents
(+)	447 (18.8)	46 (10.3)	401 (89.7)	< 0.0011	2.800	1.911-4.101
(-)	1931 (81.2)	76 (3.9)	1855 (96.1)
En-bloc resection rate	99.2%	99.1%	99.2%	0.979	0.973	0.129-7.329
R0+curative resection rate	91.9%	95.1%	97.1%	0.198	1.744	0.740-4.017
Median procedure time (min)	49 ± 30.1	50 ± 30.8	50 ± 32.2	0.8852	1.033	0.840-2.354

¹χ² test;

²t-test.