Macro- and microcirculation patterns of intrahepatic blood flow changes in patients with hereditary hemorrhagic telangiectasia

Figure 6 Quantitative (time intensity curve-) perfusion analysis within hepatic artery, portal vein, shunt region and hepatic parenchyma (two regions of interest per region) in 18 patients with diagnosed hereditary hemorrhagic telangiectasia. Percentage in relation to AUC of the hepatic artery (100%), respectively to time to peak (TTP) of the portal vein (100%). A: Obvious significant differences (P < 0.0001) in AUC values was found between the four areas, to the effect that highest values were determined in hepatic artery (100%), next up in the shunt region (83.9% ± 13.2%), subsequent in portal vein (54.2% ± 12.6%) and the lowest values were identified in the liver parenchyma (35.2% ± 13.8%); B: Concerning TTP (P < 0.02), the fastest maximal enhancement could be detected in the hepatic artery (69.8% ± 33.2%), following the shunt region (87.6% ± 29.3%), the hepatic parenchyma (102.5% ± 22.7%) and finally the portal vein (100%).