IL23R single nucleotide polymorphisms could be either beneficial or harmful in ulcerative colitis

doi:10.3748/wjg.v23.i3.447

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 21, 2017; 23(3): 447-454
Published online Jan 21, 2017. doi: 10.3748/wjg.v23.i3.447

Table 2 IL23R single nucleotide polymorphisms with statistically significant influence on the clinical picture of ulcerative colitis

SNP	Wt vs Hz	Wt vs Ho	Wt vs Hz + Ho	Wt + Hz vs Ho	Total distribution
rs2201841
Montreal-classification	0.0429^a	0.2270	0.1921	0.0217^a	0.0084^a
Iron deficiency	0.1892	0.1108	0.7476	0.0388^a	0.0299^a
Need for operation	0.0348^a	1.0000	0.0766	0.6017	0.0564
rs7517847
Bowel movements	0.0050^a	0.8183	0.0634	0.2979	0.0078^a
rs10489629
Montreal classification	0.1017	0.3906	0.4445	0.1170	0.0405^a
Weight loss	0.0652	0.0457^a	0.0169^a	0.1191	0.0350^a
rs10889677
Azathioprine	0.0116^a	0.3407	0.0136^a	0.6113	0.0285^a
Need for operation	0.0347^a	0.8491	0.0746	0.6153	0.0595

Indicates significant difference (^aP < 0.05). Hz: Heterozygous; Ho: Homozygous; Wt: Wild type; Total distribution: Wt + Hz + Ho; SNP: Single nucleotide polymorphism.

Citation: Fischer S, Kövesdi E, Magyari L, Csöngei V, Hadzsiev K, Melegh B, Hegyi P, Sarlós P. IL23R single nucleotide polymorphisms could be either beneficial or harmful in ulcerative colitis. World J Gastroenterol 2017; 23(3): 447-454
URL: https://www.wjgnet.com/1007-9327/full/v23/i3/447.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i3.447