Hwangryunhaedok-tang induces the depolarization of pacemaker potentials through 5-HT3 and 5-HT4 receptors in cultured murine small intestine interstitial cells of Cajal

Figure 3 Effects of GDP-β-S on water extract of Hwangryunhaedok-tang-induced pacemaker potential depolarizations in cultured interstitial cells of Cajal. A: When GDP-β-S (1 mmol/L) was applied in the pipette, HHTE did not depolarize the pacemaker potential. B and C: HHTE-induced responses are summarized. Bars indicate the means ± SEMs. ^eP < 0.001: Significantly different from nontreated controls. CTRL: Control; HHTE: Water extract of Hwangryunhaedok-tang.