Hwangryunhaedok-tang induces the depolarization of pacemaker potentials through 5-HT3 and 5-HT4 receptors in cultured murine small intestine interstitial cells of Cajal

Figure 1 Effects of water extract of Hwangryunhaedok-tang on the pacemaker potentials of cultured interstitial cells of Cajal from murine small intestine. A-D: HHTE (0-50 mg/mL) induced pacemaker potential depolarizations and decreased amplitudes in a concentration-dependent manner. Responses to HHTE are summarized (E-G). Bars indicate the means ± SEMs. ^eP < 0.001: significantly different from the control. CTRL: Control; HHTE: Water extract of Hwangryunhaedok-tang.