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©The Author(s) 2017.
World J Gastroenterol. Aug 7, 2017; 23(29): 5364-5370
Published online Aug 7, 2017. doi: 10.3748/wjg.v23.i29.5364
Published online Aug 7, 2017. doi: 10.3748/wjg.v23.i29.5364
Table 4 Association between rs4268033 and phenotype of ulcerative colitis
Genotype (n) | AA vs others | ||||
GG | GA | AA | OR (95%CI) | P value | |
Controls (748) | 366 | 324 | 58 | Reference | - |
Age of onset | |||||
20 (31) | 16 | 12 | 3 | 2.06 (0.499-8.52) | 0.32 |
21 (176) | 76 | 71 | 29 | 2.51 (1.51-4.19) | 0.0004 |
Unknown (19) | |||||
Clinical type | |||||
Not continuous (124) | 51 | 52 | 21 | 2.92 (1.63-5.25) | 0.0003 |
Continuous (97) | 46 | 36 | 15 | 2.32 (1.20-4.48) | 0.012 |
Unknown (5) | |||||
Extension | |||||
Not total colitis (115) | 50 | 46 | 19 | 2.72 (1.48-5.00) | 0.0013 |
Total colitis (105) | 49 | 41 | 15 | 2.18 (1.14-4.16) | 0.019 |
Unknown (6) | |||||
Hospitalization | |||||
None (139) | 59 | 59 | 21 | 2.34 (1.32-4.14) | 0.0035 |
One time £ (76) | 36 | 27 | 13 | 2.91 (1.42-5.97) | 0.0034 |
Unknown (11) | |||||
Past max. UCDAI score | |||||
8 (135) | 56 | 58 | 21 | 2.41 (1.36-4.27) | 0.0025 |
9 (81) | 40 | 27 | 14 | 3.01 (1.49-6.05) | 0.002 |
Unknown (10) |
- Citation: Arisawa T, Nakamura M, Otsuka T, Jing W, Sakurai N, Takano H, Hayashi T, Ota M, Nomura T, Hayashi R, Shimasaki T, Tahara T, Shibata T. Genetic polymorphisms of MAFK, encoding a small Maf protein, are associated with susceptibility to ulcerative colitis in Japan. World J Gastroenterol 2017; 23(29): 5364-5370
- URL: https://www.wjgnet.com/1007-9327/full/v23/i29/5364.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i29.5364