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©The Author(s) 2017.
World J Gastroenterol. Aug 7, 2017; 23(29): 5364-5370
Published online Aug 7, 2017. doi: 10.3748/wjg.v23.i29.5364
Published online Aug 7, 2017. doi: 10.3748/wjg.v23.i29.5364
Table 3 Association between MAFK polymorphisms and ulcerative colitis
Genotype (n) | AA vs others | Genotype (n) | CC vs others | Genotype (n) | TT vs others | ||||||||||
GG | GA | AA | OR (95%CI); P value | TT | TC | CC | OR (95%CI); P value | CC | CT | TT | OR (95%CI); P value | ||||
rs4268033 G>A | |||||||||||||||
Controls (748) | 366 | 324 | 58 | Reference | - | ||||||||||
IBM controls (358) | 184 | 156 | 18 | 0.682 (0.402-1.16); P = 0.16 | Reference | ||||||||||
UC cases (226) | 101 | 89 | 36 | 2.63 (1.61-4.30); P = 0.0001 | 3.54 (1.82-6.88); P = 0.0002 | ||||||||||
rs3735656 T>C | |||||||||||||||
Controls (748) | 329 | 346 | 73 | Reference | - | ||||||||||
IBM controls (358) | 168 | 162 | 28 | 0.789 (0.503-1.24); P = 0.30 | Reference | ||||||||||
UC cases (174) | 103 | 90 | 33 | 1.81 (1.12-2.94); P = 0.015 | 2.14 (1.16-3.95); P = 0.015 | ||||||||||
rs10226620 C>T | |||||||||||||||
Controls (748) | 345 | 328 | 75 | Reference | - | ||||||||||
IBM controls (358) | 171 | 159 | 28 | 0.764 (0.488-1.20); P = 0.24 | Reference | ||||||||||
UC cases (174) | 104 | 94 | 28 | 1.37 (0.822 - 2.28); P = 0.23 | 1.57 (0.827 - 3.00); P = 0.17 |
- Citation: Arisawa T, Nakamura M, Otsuka T, Jing W, Sakurai N, Takano H, Hayashi T, Ota M, Nomura T, Hayashi R, Shimasaki T, Tahara T, Shibata T. Genetic polymorphisms of MAFK, encoding a small Maf protein, are associated with susceptibility to ulcerative colitis in Japan. World J Gastroenterol 2017; 23(29): 5364-5370
- URL: https://www.wjgnet.com/1007-9327/full/v23/i29/5364.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i29.5364