Bone marrow-derived monocyte infusion improves hepatic fibrosis by decreasing osteopontin, TGF-β1, IL-13 and oxidative stress

doi:10.3748/wjg.v23.i28.5146

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2017; 23(28): 5146-5157
Published online Jul 28, 2017. doi: 10.3748/wjg.v23.i28.5146

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Figure 5 Immunohistochemistry for detection of osteopontin in histological sections. A-D: Control (A), saline-treated (B), BMMCs-treated (C) and CD11b⁺CD14⁺ monocyte-treated (D) groups of mice (magnification × 200); E: Levels of hepatic OPN at 2 mo after treatment with CD11b⁺CD14⁺ monocytes. ^aP < 0.05. OPN: Osteopontin. BMMCs: Bone marrow mononuclear cells.

Citation: de Souza VCA, Pereira TA, Teixeira VW, Carvalho H, de Castro MCAB, D’assunção CG, de Barros AF, Carvalho CL, de Lorena VMB, Costa VMA, Teixeira ÁAC, Figueiredo RCBQ, de Oliveira SA. Bone marrow-derived monocyte infusion improves hepatic fibrosis by decreasing osteopontin, TGF-β1, IL-13 and oxidative stress. World J Gastroenterol 2017; 23(28): 5146-5157
URL: https://www.wjgnet.com/1007-9327/full/v23/i28/5146.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i28.5146