Bone marrow-derived monocyte infusion improves hepatic fibrosis by decreasing osteopontin, TGF-β1, IL-13 and oxidative stress

Figure 3 Photomicrographs of histological liver sections stained with picro-Sirius red. A-D: The figure shows hepatic collagens in (A) control mice, mice after CCl₄ administration and treatment with (B) saline, (C) BMMCs and (D) BMMC-derived monocytes (picro-Sirius red; magnification × 100); E: Morphometric evaluation of picro-Sirius Red-stained sections; F: Hydroxyproline in liver fragments of mice undergoing cell transplantation; G: Kupffer cell count in hematoxylin-eosin-stained histological liver sections from mice who underwent CD11b⁺CD14⁺ monocyte therapy and BMMC-treated mice. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001. BMMCs: Bone marrow mononuclear cells.