Bone marrow-derived monocyte infusion improves hepatic fibrosis by decreasing osteopontin, TGF-β1, IL-13 and oxidative stress

Figure 2 Schematic flowchart of experimental design. A: Male C57BL/6 mice underwent chronic administration of CCl₄ and EtOH solutions for 6 mo; B: Bone marrow mononuclear cells were harvested from C57BL/6 donor mice for CD11b⁺ monocyte isolation using immunomagnetic separation; C: Chronically liver-damaged mice underwent cell therapy; D: After 2 mo, effects of the treatment were evaluated using morphometric, biochemical, immunohistochemistry and sandwich ELISA analysis.