Myo-inositol reduces β-catenin activation in colitis

Figure 4 Myo-inositol reduces the number of pβ-cat-positive cells in ulcerative colitis patients. A: Representative low power images of biopsies stained for pβ-cat from a patient before and after 90 d of myo-inositol treatment. B: pβ-cat staining in an area of LGD; C: pβ-cat staining in a non-dysplastic area adjacent to LGD. Note the HFC containing multiple pβ-cat-positive nuclei; D: Graphic representation of the percent of crypts from each patient pre- and post-treatment containing 2 or more pβ-cat-positive nuclei; E: The percent of all high powered fields of view (FOV) containing HFC in biopsies from each patient. N: Normal tissue; LGD: Low grade dysplasia.