Gastrointestinal neuroendocrine peptides/amines in inflammatory bowel disease

Figure 8 Colonic densities of (A) peptide YY-positive cells and (B) oxyntomodulin (enteroglucagon)-positive cells in control rats, in rats with trinitrobenzene sulfonic acid (TNBS)-induced colitis, and in rats with TNBS-induced colitis treated with 3-[(dodecylthiocarbonyl)-methyl]-glutarimide (DTCM-G, an activator protein-1 inhibitor) and dehydroxymethylepoxyquinomicin (DHMEQ, a nuclear factor-κB inhibitor). Densities of PYY-positive and oxyntomodulin-positive cells in each rat of the TNBS group (C), and their correlation (D). ^eP < 0.001 vs controls. Reproduced from reference 274 with permission from the authors and the publisher. PYY: Peptide YY.