Observational Study
Copyright ©The Author(s) 2017.
World J Gastroenterol. Jul 28, 2017; 23(28): 5216-5228
Published online Jul 28, 2017. doi: 10.3748/wjg.v23.i28.5216
Table 6 Comparison of the gastroesophageal reflux and dyspepsia-therapeutic efficacy and satisfaction test scores between responders and non-responders based on a "residual symptom rate ≤ 50%" definition
Before Tx
After 4 wk PPI Tx
Δ (0W-4W)
Responder definition byResponder (n = 153)
Non-responder (n = 41)
Cohen's dP valueResponder (n = 153)
Non-responder (n = 41)
Cohen's dP valueResponder (n = 153)
Non-responder (n = 41)
Cohen's dP value
Residual Sx 50% ≥meanSDmeanSDmeanSDmeanSDmeanSDmeanSD
Q1. Heartburn3.791.293.341.090.360.0251.450.613.051.072.21< 0.0001-2.341.24-0.290.871.76< 0.0001
Q2. Acid regurgitation3.311.322.851.370.340.0601.370.572.781.241.86< 0.0001-1.931.25-0.071.171.51< 0.0001
GERD-SS3.551.193.100.990.390.0141.410.532.911.082.21< 0.0001-2.141.11-0.180.711.89< 0.0001
Q3. Epigastric pain or burning3.121.423.271.18-0.5091.510.842.731.101.36< 0.0001-1.611.41-0.541.030.81< 0.0001
Q4. Postprandial fullness3.051.393.151.15-0.6361.790.962.611.180.81< 0.0001-1.251.32-0.541.160.560.001
Q5. Early satiation2.261.382.281.20-0.9501.660.852.171.050.570.004-0.601.13-0.100.900.460.003
FD-SS2.891.172.980.94-0.6221.620.742.560.851.24< 0.0001-1.271.06-0.420.820.84< 0.0001
Q6. Eating1.951.052.071.15-0.5501.340.691.680.880.470.023-0.610.88-0.391.020.250.206
Q7. Sleeping2.171.082.051.05-0.5141.180.491.660.880.800.001-0.991.02-0.390.860.610.000
Q8. Daily activity1.991.031.980.89-0.9091.240.61.680.820.680.001-0.751.05-0.300.850.450.005
Q9. Mood2.601.072.460.98-0.4331.430.742.100.830.88< 0.0001-1.171.06-0.370.800.80< 0.0001
Dissatisfaction for daily life-SS2.180.832.110.84-0.6501.300.521.780.690.86< 0.0001-0.880.77-0.360.640.71< 0.0001
Effect sizeSmallMediumLarge
Cohen's d0.2 ≤0.5 ≤0.8 ≤