Copyright
©The Author(s) 2017.
World J Gastroenterol. Jul 28, 2017; 23(28): 5216-5228
Published online Jul 28, 2017. doi: 10.3748/wjg.v23.i28.5216
Published online Jul 28, 2017. doi: 10.3748/wjg.v23.i28.5216
Before Tx | After 4 wk PPI Tx | Δ (0W-4W) | ||||||||||||||||
Responder definition by | Responder (n = 153) | Non-responder (n = 41) | Cohen's d | P value | Responder (n = 153) | Non-responder (n = 41) | Cohen's d | P value | Responder (n = 153) | Non-responder (n = 41) | Cohen's d | P value | ||||||
Residual Sx 50% ≥ | mean | SD | mean | SD | mean | SD | mean | SD | mean | SD | mean | SD | ||||||
Q1. Heartburn | 3.79 | 1.29 | 3.34 | 1.09 | 0.36 | 0.025 | 1.45 | 0.61 | 3.05 | 1.07 | 2.21 | < 0.0001 | -2.34 | 1.24 | -0.29 | 0.87 | 1.76 | < 0.0001 |
Q2. Acid regurgitation | 3.31 | 1.32 | 2.85 | 1.37 | 0.34 | 0.060 | 1.37 | 0.57 | 2.78 | 1.24 | 1.86 | < 0.0001 | -1.93 | 1.25 | -0.07 | 1.17 | 1.51 | < 0.0001 |
GERD-SS | 3.55 | 1.19 | 3.10 | 0.99 | 0.39 | 0.014 | 1.41 | 0.53 | 2.91 | 1.08 | 2.21 | < 0.0001 | -2.14 | 1.11 | -0.18 | 0.71 | 1.89 | < 0.0001 |
Q3. Epigastric pain or burning | 3.12 | 1.42 | 3.27 | 1.18 | - | 0.509 | 1.51 | 0.84 | 2.73 | 1.10 | 1.36 | < 0.0001 | -1.61 | 1.41 | -0.54 | 1.03 | 0.81 | < 0.0001 |
Q4. Postprandial fullness | 3.05 | 1.39 | 3.15 | 1.15 | - | 0.636 | 1.79 | 0.96 | 2.61 | 1.18 | 0.81 | < 0.0001 | -1.25 | 1.32 | -0.54 | 1.16 | 0.56 | 0.001 |
Q5. Early satiation | 2.26 | 1.38 | 2.28 | 1.20 | - | 0.950 | 1.66 | 0.85 | 2.17 | 1.05 | 0.57 | 0.004 | -0.60 | 1.13 | -0.10 | 0.90 | 0.46 | 0.003 |
FD-SS | 2.89 | 1.17 | 2.98 | 0.94 | - | 0.622 | 1.62 | 0.74 | 2.56 | 0.85 | 1.24 | < 0.0001 | -1.27 | 1.06 | -0.42 | 0.82 | 0.84 | < 0.0001 |
Q6. Eating | 1.95 | 1.05 | 2.07 | 1.15 | - | 0.550 | 1.34 | 0.69 | 1.68 | 0.88 | 0.47 | 0.023 | -0.61 | 0.88 | -0.39 | 1.02 | 0.25 | 0.206 |
Q7. Sleeping | 2.17 | 1.08 | 2.05 | 1.05 | - | 0.514 | 1.18 | 0.49 | 1.66 | 0.88 | 0.80 | 0.001 | -0.99 | 1.02 | -0.39 | 0.86 | 0.61 | 0.000 |
Q8. Daily activity | 1.99 | 1.03 | 1.98 | 0.89 | - | 0.909 | 1.24 | 0.6 | 1.68 | 0.82 | 0.68 | 0.001 | -0.75 | 1.05 | -0.30 | 0.85 | 0.45 | 0.005 |
Q9. Mood | 2.60 | 1.07 | 2.46 | 0.98 | - | 0.433 | 1.43 | 0.74 | 2.10 | 0.83 | 0.88 | < 0.0001 | -1.17 | 1.06 | -0.37 | 0.80 | 0.80 | < 0.0001 |
Dissatisfaction for daily life-SS | 2.18 | 0.83 | 2.11 | 0.84 | - | 0.650 | 1.30 | 0.52 | 1.78 | 0.69 | 0.86 | < 0.0001 | -0.88 | 0.77 | -0.36 | 0.64 | 0.71 | < 0.0001 |
Effect size | Small | Medium | Large | |||||||||||||||
Cohen's d | 0.2 ≤ | 0.5 ≤ | 0.8 ≤ |
- Citation: Nakada K, Matsuhashi N, Iwakiri K, Oshio A, Joh T, Higuchi K, Haruma K. Development and validation of a simple and multifaceted instrument, GERD-TEST, for the clinical evaluation of gastroesophageal reflux and dyspeptic symptoms. World J Gastroenterol 2017; 23(28): 5216-5228
- URL: https://www.wjgnet.com/1007-9327/full/v23/i28/5216.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i28.5216