Sex-influenced association of non-alcoholic fatty liver disease with colorectal adenomatous and hyperplastic polyps

Table 3 Adjusted ORs and 95%CIs of clinical variables on the risk of colorectal polyps, adenomatous polyps and hyperplastic polyps based on multinomial logistic regression

Polyps	Model A	Model B	Model C
	OR (95%CI)	OR (95%CI)	OR (95%CI)
Colorectal polyps
NAFLD	1.49 (1.26-1.76)b	1.28 (1.07-1.52)a	1.26 (1.05-1.51)a
Gender		2.81 (2.37-3.34)b	2.76 (2.32-3.29)b
Age		1.06 (1.05-1.06)b	1.06 (1.05-1.06)b
Smoking		1.15 (0.98-1.35)	1.15 (0.97-1.38)
Alcohol			1.01 (0.86-1.20)
MS			1.12 (0.90-1.40)
Adenomatous polyps
NAFLD	1.49 (1.18-1.87)a	1.29 (1.02-1.64)a	1.28 (1.01-1.64)a
Gender		2.83 (2.22-3.61)b	2.78 (2.18-3.55)b
Age		1.07 (1.06-1.08)b	1.07 (1.06-1.08)b
Smoking		1.09 (0.88-1.36)	1.06 (0.84-1.35)
Alcohol			1.09 (0.87-1.37)
MS			1.02 (0.76-1.38)
Hyperplastic polyps
NAFLD	1.73 (1.31-2.29)b	1.40 (1.05-1.86)a	1.35 (1.01-1.82)a
Gender		3.23 (2.33-4.47)b	3.12 (2.25-4.33)b
Age		1.03 (1.02-1.05)b	1.03 (1.02-1.05)b
Smoking		1.30 (1.00-1.70)a	1.27 (0.95-1.70)
Alcohol			1.09 (0.82-1.44)
MS			1.13 (0.79-1.63)

Model A is univariate analysis; Model B is adjusted for gender, age and smoking; Model C is adjusted for gender, age, smoking, alcohol and MS.

^aP < 0.05;

^bP < 0.001. NAFLD: Non-alcoholic fatty liver disease; MS: Metabolic syndrome.