Sex-influenced association of non-alcoholic fatty liver disease with colorectal adenomatous and hyperplastic polyps

Table 2 Demographic and clinical characteristics of 2430 males and 1256 females according to colonoscopic findings n (%)

Characteristic of males	Polyp-free	Colorectal polyps	P value vs Polyp-free	Adenomatous polyps	P value vs Polyp-free	Hyperplastic polyps	P value vs Polyp-free
Colonoscopic findings of 2430 males
	1487 (61.2)	943 (38.8)		393 (16.2)		239 (9.8)
Age (yr)	44.61 ± 9.91	50.18 ± 9.67	< 0.001	51.71 ± 9.54	< 0.001	47.56 ± 8.90	< 0.001
Weight (kg)	69.46 ± 10.18	70.88 ± 10.20	0.001	70.27 ± 10.12	0.164	71.47 ± 10.74	0.005
Height (cm)	169.13 ± 5.56	168.88 ± 5.80	0.305	168.28 ± 6.04	0.012	169.44 ± 5.72	0.427
BMI (kg/m2)	24.28 ± 3.22	24.81 ± 3.06	< 0.001	24.77 ± 3.03	0.006	24.85 ± 3.22	0.011
SBP (mmHg)	127.29 ± 16.24	130.47 ± 17.83	< 0.001	131.97 ± 18.29	< 0.001	127.82 ± 16.88	0.639
DBP (mmHg)	76.44 ± 11.75	78.14 ± 12.03	0.001	78.77 ± 11.93	0.001	77.57 ± 12.11	0.173
FPG (mmol/L)	4.86 ± 1.26	5.06 ± 1.49	0.001	5.04 ± 1.46	0.012	4.96 ± 1.42	0.233
TG (mmol/L)	2.14 ± 2.04	2.15 ± 1.95	0.920	2.16 ± 2.24	0.878	2.14 ± 1.24	0.987
TC (mmol/L)	5.42 ± 1.16	5.42 ± 1.12	0.954	5.45 ± 1.24	0.686	5.49 ± 1.08	0.374
HDL-C (mmol/L)	1.22 ± 0.28	1.22 ± 0.29	0.892	1.24 ± 0.30	0.244	1.21 ± 0.27	0.597
LDL-C (mmol/L)	3.26 ± 0.86	3.26 ± 0.84	0.829	3.24 ± 0.83	0.632	3.34 ± 0.90	0.221
ALT (IU/L)	34.71 ± 33.63	35.31 ± 29.49	0.657	35.54 ± 23.59	0.649	35.2 ± 27.26	0.834
AST (IU/L)	29.00 ± 17.83	30.22 ± 19.06	0.115	30.37 ± 12.31	0.155	29.32 ± 13.41	0.796
NAFLD	355 (23.9)	268 (28.4)	0.014	116 (29.5)	0.028	72 (30.1)	0.038
MS	194 (13.3)	156 (17.0)	0.018	64 (15.8)	0.123	37 (18.3)	0.334
Smoking	465 (31.4)	327 (34.9)	0.076	127 (32.4)	0.717	91 (38.2)	0.045
Alcohol	577 (39.0)	377 (40.3)	0.536	153 (39.0)	0.995	100 (42.0)	0.379
Colonoscopic findings of 1256 females
	1014 (80.7)	242 (19.3)		105 (8.4)		49 (3.9)
Age (yr)	46.73 ± 9.97	51.68 ± 10.96	< 0.001	51.99 ± 10.68	< 0.001	51.10 ± 9.50	0.003
Weight (kg)	56.62 ± 8.03	58.41 ± 8.27	0.002	57.34 ± 8.61	0.385	60.42 ± 7.01	0.001
Height (cm)	158.04 ± 5.32	157.62 ± 5.16	0.268	157.08 ± 5.46	0.080	157.89 ± 4.21	0.840
BMI (kg/m2)	22.66 ± 2.96	23.50 ± 3.05	< 0.001	23.21 ± 3.06	0.073	24.24 ± 2.66	< 0.001
SBP (mmHg)	120.23 ± 19.07	128.13 ± 20.13	< 0.001	125.21 ± 19.59	0.012	127.25 ± 22.56	0.013
DBP (mmHg)	69.12 ± 11.70	72.40 ± 11.31	< 0.001	71.19 ± 11.03	0.086	72.63 ± 12.27	0.041
FPG (mmol/L)	4.66 ± 0.90	4.80 ± 0.99	0.037	4.80 ± 1.07	0.147	4.80 ± 1.06	0.318
TG (mmol/L)	1.27 ± 0.80	1.46 ± 0.92	0.002	1.30 ± 0.66	0.716	1.65 ± 1.11	0.002
TC (mmol/L)	5.25 ± 1.05	5.52 ± 1.10	< 0.001	5.43 ± 1.09	0.088	5.72 ± 1.17	0.002
HDL-C (mmol/L)	1.48 ± 0.33	1.42 ± 0.31	0.008	1.43 ± 0.31	0.114	1.41 ± 0.28	0.123
LDL-C (mmol/L)	3.09 ± 0.85	3.33 ± 0.91	< 0.001	3.30 ± 0.87	0.017	3.45 ± 1.00	0.004
ALT (IU/L)	21.15 ± 19.93	20.13 ± 11.46	0.451	17.74 ± 9.29	3.000	21.76 ± 13.28	0.835
AST (IU/L)	24.64 ± 12.98	23.71 ± 8.56	0.286	22.62 ± 6.73	0.121	25.00 ± 13.10	0.848
NAFLD	93 (9.2)	23 (9.5)	0.873	6 (5.7)	0.160	7 (14.3)	0.324
MS	52 (5.3)	24 (10.2)	0.021	9 (8.8)	0.227	7 (14.3)	0.084
Smoking	197 (19.6)	46 (19.2)	0.884	24 (23.3)	0.369	10 (20.4)	0.887
Alcohol	277 (27.5)	68 (28.3)	0.804	38 (36.9)	0.063	18 (36.7)	0.201

BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; FPG: Fasting plasma glucose; TG: Triglyceride; TC: Total cholesterol; HDL-C: High density lipoprotein-cholesterol; LDL-C: Low density lipoprotein-cholesterol; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; NAFLD: Non-alcoholic fatty liver disease; MS: Metabolic syndrome.