Clinical significance of glycemic parameters on venous thromboembolism risk prediction in gastrointestinal cancer

Table 3 Receiver operating characteristics and Bayesian analysis of venous thromboembolism predictive value of glycemic parameters

	Fasting blood glucose	Fasting insulin	HOMA	HbA1c
AUC (SE)	0.636 (0.06)	0.630 (0.05)	0.647 (0.05)	0.574 (0.06)
95%CI	0.582-0.687	0.576-0.681	0.593-0.697	0.519-0.627
Criterion1	103 mg/dL	12 μIU/mL	2.6	6.0%
Sensitivity	75%	75%	81%	59%
Specificity	65%	51%	48%	63%
PPV	18%	14%	14%	14%
NPV	96%	95%	96%	94%
+LR (CI)	2.12 (1.54-2.57)	1.54 (1.13-1.85)	1.56 (1.19-1.81)	1.60 (1.07-2.13)
-LR (CI)	0.39 (0.19-0.68)	0.49 (0.23-0.87)	0. 39 (0.16-0.78)	0.65 (0.38-0.96)
P value2	0.0135	0.0128	0.0045	0.1989

¹Corresponding with highest Youden index;

²Significance level P (Area = 0.5). AUC: Area under the curve; PPV: Positive predictive value; NPV: Negative predictive value; +LR: Positive likelihood ratio; -LR: Negative likelihood ratio.