Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection

Table 3 Multivariate analysis of risk factors associated with postoperative complications

Characteristic	OR	95%CI	P value
Age ≥ 75 yr	1.053	0.248-4.470	0.945
Sex	0.572	0.237-1.380	0.214
BMI of < 18.5 kg/m2	0.147	0.013-1.666	0.122
Comorbidities
Diabetes mellitus	1.234	0.322-4.726	0.759
Hypertension	0.989	0.397-2.463	0.981
Preoperative serum albumin of < 35 g/L	0.914	0.897-1.067	0.093
Preoperative hemoglobin of < 120 g/L	1.804	0.748-4.353	0.189
Preoperative CRP of ≥ 10 g/L	1.008	0.210-4.840	0.993
CA 19-9 of ≥ 37 ng/mL	1.197	0.431-3.327	0.730
CEA of ≥ 5 ng/mL	0.794	0.233-2.706	0.713
Lymphocyte count of ≥ 3 × 109/L	0.192	0.018-2.048	0.172
CRP on POD 3 in mg/L	4.296	1.887-9.780	0.001
△ALB of ≥ 14.0%	17.957	6.073-53.095	< 0.001
ASA of ≥ 3	0.929	0.406-2.127	0.861
Clinical stage of ≥ II	1.198	0.355-2.286	0.109
Mode of surgical approach	1.737	0.576-5.235	0.327
Type of resection	0.791	0.506-1.896	0.063
Degree of lymph node dissection ≥ 2	3.485	1.163-10.446	0.026
Operation time of ≥ 250 min	1.448	0.624-3.355	0.389
Blood loss of ≥ 200 mL	1.418	0.636-3.160	0.393

∆ALB: (Albumin level before surgery-albumin on POD 1)/albumin level before surgery × 100%; ASA: American Society of Anesthesiologists; BMI: Body mass index; CA 19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; CRP: C-reactive protein; POD: Postoperative day.