Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection

Table 2 Univariate analysis of risk factors associated with postoperative complications

Characteristic	OR	95%CI	P value
Age ≥ 75 yr	1.330	0.476-3.715	0.586
Sex	0.642	0.342-1.202	0.166
BMI of < 18.5 kg/m2	0.277	0.034-2.232	0.228
Comorbidities
Diabetes mellitus	3.259	1.128-9.414	0.029
Hypertension	0.728	0.382-1.389	0.336
Preoperative serum albumin of < 35 g/L	1.048	1.018-1.109	0.015
Preoperative hemoglobin of < 120 g/L	1.487	0.817-2.705	0.194
Preoperative CRP of ≥ 10 g/L	1.336	0.512-3.486	0.553
CA 19-9 of ≥ 37 ng/mL	1.328	0.647-2.723	0.439
CEA of ≥ 5 ng/mL	1.177	0.483-2.865	0.720
Lymphocyte count of ≥ 3 × 109/L	0.314	0.038-2.560	0.279
CRP on POD 3 in mg/L	4.653	2.435-8.889	< 0.001
△ALB of ≥ 14.0%	16.837	6.403-44.275	< 0.001
ASA of ≥ 3	1.007	0.559-1.815	0.981
Clinical stage of ≥ II	1.798	1.255-2.686	0.009
Mode of surgical approach	1.206	0.588-2.475	0.610
Type of resection	1.291	1.006-1.896	0.013
Degree of lymph node dissection ≥ 2	2.263	0.948-5.399	0.066
Operation time of ≥ 250 min	1.621	0.896-2.931	0.110
Blood loss of ≥ 200 mL	1.417	0.758-2.651	0.275

∆ALB: (Albumin level before surgery-albumin on POD 1)/albumin level before surgery × 100%; ASA: American Society of Anesthesiologists; BMI: Body mass index; CA 19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; CRP: C-reactive protein; POD: Postoperative day.