Genetic polymorphisms predict response to anti-tumor necrosis factor treatment in Crohn’s disease

Table 1 Hardy weinberg equilibrium n (%)

	Genotype distribution		Hardy Weinberg equilibrium
SNP	Genotype	Frequency	Expected frequency (n)	P value1
ATG16L1 rs10210302	CC	25 (21.0)	24	NS
	TC	57 (47.9)	59
	TT	37 (31.1)	36
ATG16L1 rs2241880	AA	27 (22.5)	26	NS
	GA	57 (47.5)	60
	GG	36 (30.0)	35
Fas Ligand rs763110	CC	42 (36.5)	41	NS
	TC	54 (47.0)	55
	TT	19 (16.5)	18
IBD5 rs2522057	CC	35 (29.2)	29	0.045
	GC	49 (40.8)	60
	GG	36 (30.0)	31
FCGR 3A rs396991	AA	70 (58.3)	62	0.0005
	AC	33 (27.5)	48
	CC	17 (14.2)	9
TNF gene (-308) rs1800629	AA	4 (3.4)	3	NS
	GA	31 (26.1)	33
	GG	84 (70.6)	83
TNF gene (-238) rs361525	AA	2 (1.7)	1	NS
	GA	15 (12.5)	17
	GG	103 (85.8)	102

¹Calculated using χ². TNF: Tumor necrosis factor; SNPs: Single nucleotide polymorphisms.