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©The Author(s) 2017.
World J Gastroenterol. Jul 21, 2017; 23(27): 4856-4866
Published online Jul 21, 2017. doi: 10.3748/wjg.v23.i27.4856
Published online Jul 21, 2017. doi: 10.3748/wjg.v23.i27.4856
Table 2 Frequency of genetic mutations in gastrointestinal stromal tumors
| KIT mutation (about 85%) | PDGFRA mutation (about 5%) | BRAF mutation (< 1%) | SDH mutation (12%-15% adult, 90% pediatric GIST) |
| Exon 11 (about 70%) | Exon 18 (about 5%) | Exon 15 V600E | Subunit B, C and D |
| Exon 9 (10%-15%) | Exon 12 (1%) | ||
| Exon 13 (1%-3%) | Exon 14 (< 0.5%) | ||
| Exon 17 (1%) | Exon 18 D842V (about 0%) |
- Citation: Lim KT, Tan KY. Current research and treatment for gastrointestinal stromal tumors. World J Gastroenterol 2017; 23(27): 4856-4866
- URL: https://www.wjgnet.com/1007-9327/full/v23/i27/4856.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i27.4856