Divergent expression of bacterial wall sensing Toll-like receptors 2 and 4 in colorectal cancer

Figure 2 Immunohistochemical stainings for toll-like receptor 2 (A) and toll-like receptor 4 (B) in a case of colorectal carcinoma. Moderate to strong TLR2 expression in the carcinoma cells is present in both the invasive front (lower part of the Figure) and in the tumor bulk (upper part of the Figure; A). In contrast, corresponding view showing TLR4 staining indicates that expression is moderate to weak in the front (lower part) and weak to negative in the bulk (upper part; B). Reference lines, 50 μm. TLR: Toll-like receptor.