Effect of EPEC endotoxin and bifidobacteria on intestinal barrier function through modulation of toll-like receptor 2 and toll-like receptor 4 expression in intestinal epithelial cell-18

Figure 2 Toll-like receptor 2 and toll-like receptor 4 mRNA expression in intestinal epithelial cell-18 cells after treatment with EPEC endotoxin and bifidobacteria for 16 h. TLR2 and TLR4 mRNA expression was significantly upregulated in the EPEC group. A: TLR2 mRNA expression in B.infantis, B.longum and B.youthgroups were significantly lower than in the control groups; B: TLR4 mRNA expression in B.bifidum and B.youth groups were significantly lower than in the normal control group.1, 2, 3, 4, 5 and 6 represent normal control, EPEC, B.infantis, B.longum, B.bifidum and B. youth groups, respectively. ^aP < 0.05, ^bP < 0.001 vs the control group. TLRs: Toll-like receptors.