Helicobacter pylori vacA genotype is a predominant determinant of immune response to Helicobacter pylori CagA

Figure 2 Correlation between anti-CagA-IgG and anti-Helicobacter pylori IgG and vacA s/m polymorphisms. A: Quantitative values for anti-Helicobacter pylori IgG and anti-CagA-IgG were correlated in patients with positive serology (n = 30) using Pearson’s test; B: Patients with available data to vacA s1/2m1/2 polymorphisms were divided in subgroups dependent on s/m subtype. Anti-CagA-IgG values were sorted in increasing order. Dotted line shows the cut-off for seropositivity of the test (6.25 U/mL).