Fibrinogen deficiency suppresses the development of early and delayed radiation enteropathy

Figure 1 PCR analysis of mouse genotype and fibrinogen levels in plasma and intestinal tissue of Fib^+/+, Fib^+/- and Fib^-/- mice. A: Representative agarose gel image showing DNA marker (Lane 1), single band at around 376 base pair (Lane 2 and 3) that denotes Fib^+/+ mice, double bands, one at around 376 bp and the other is at around 283 bp (Lane 4 and 5), which signify Fib^+/- mice, and single band at around 283 bp (Lane 6 and 7) that represents Fib^-/- mice; B: Plasma fibrinogen level in un-irradiated Fib^+/+ (n = 5), Fib^+/- (n = 6) and Fib^-/- (n = 5) mice as detected by enzyme-linked immunosorbent assay (ELISA) assay; C: Fibrinogen level in the intestinal tissue of un-irradiated Fib^+/+ (n = 6), Fib^+/- (n = 10) and Fib^-/- (n = 3) mice as detected by ELISA assay.