Divergent expression of bacterial wall sensing Toll-like receptors 2 and 4 in colorectal cancer

Table 4 Comparison of mean intensities of immunostainings between toll-like receptors 2 and 4

	Intensity, mean ± SD	P value	Histoscore, mean ± SD	P value	n
Tumour bulk
TLR2	2.3 ± 0.6	< 0.001	225 ± 64	< 0.001	117
TLR4	2.0 ± 0.7		198 ± 73		117
Invasive front
TLR2	2.3 ± 0.6	0.55	225 ± 66	0.83	116
TLR4	2.3 ± 0.6		223 ± 66		116
Lymph node
TLR2	1.8 ± 0.7	< 0.001	180 ± 71	< 0.001	43
TLR4	2.4 ± 0.7		241 ± 70		43
Normal mucosa
TLR2	1.4 ± 0.7	< 0.001	129 ± 72	< 0.001	114
TLR4	2.6 ± 0.6		243 ± 79		114

N values vary due to missing samples. TLR: Toll-like receptor.